GDP-甘露糖 3',5'-差向异构酶(GME)
在抗坏血酸途径中, GME 基因编码 GDP-甘露糖-3', 5'-差向异构酶，催化 GDP-D-甘露糖转化为 GDP-L-半乳糖。这是抗坏血酸生物合成的关键步骤。GME 在调节 GDP - L - 半乳糖的供应方面起着至关重要的作用, GDP - 半乳糖是抗坏血酸的直接前体。通过控制这种前体的水平, GME 影响抗坏血酸的最终合成和含量，从而有助于维持生物体内抗坏血酸代谢平衡。
GDP-Mannose 3,5-Epimerase(GME)
In the ascorbic acid pathway, the GME gene encodes GDP - mannose - 3',5'-epimerase, which catalyzes the conversion of GDP - D - mannose to GDP - L - galactose. This is a key step in the biosynthesis of ascorbic acid. GME plays a crucial role in regulating the supply of GDP - L - galactose, which is a direct precursor of ascorbic acid. By controlling the level of this precursor, GME affects the final synthesis and content of ascorbic acid, thus contributing to the maintenance of the ascorbic acid metabolic balance in organisms.
| 拟南芥(Arabidopsis thaliana) | AtGME |
| 番茄(Solanum Lycopersicum) | SlGME1(Solyc01g097340.3.1);SlGME2(Solyc09g082990.3.1) |
| 葡萄(Vitis vinifera) | VvGME1(XP_034686117.1);VvGME2(XP_034686116.1);VvGME3(XP_034707730.1);VvGME4(XP_034707729.1) |
| 中华猕猴桃'红阳' (Actinidia chinensis cv 'Hongyang') |
AcGME1(Actinidia40102.t1);AcGME2(Actinidia04499.t1);AcGME3(Actinidia18358.t1) |
| 中华猕猴桃'Red5' (Actinidia chinensis cv 'Red5') |
AcGME1(Acc04223.1);AcGME2(Acc27374.1) |
| 中华猕猴桃'东红' (Actinidia chinensis cv 'Donghong') |
AcGME1(Ach03g02570DH);AcGME2(Ach24g10180DH);AcGME3(Ach01g09920DH) |
| 毛花猕猴桃'华特' (Actinidia eriantha 'White') |
AeGME1(DTZ79_24g13050);AeGME2(DTZ79_24g03690);AeGME3(DTZ79_03g18610);AeGME4(DTZ79_01g04910) |
| 野生毛花猕猴桃 (Actinidia eriantha WT) |
AeGME1(evm.model.scaf_123.300);AeGME2(evm.model.scaf_93.203);AeGME3(evm.model.scaf_61.139) |
| 毛花猕猴桃'赣绿1号' (Actinidia eriantha 'Ganlv1') |
AeGME1(Chr_23G333.2);AeGME2(Chr_01G1746.1);AeGME3(Chr_13G420.1) |
| 山梨猕猴桃(Actinidia rufa) | ArGME1(lcl|BJWL01000024.1_prot_GFZ14164.1_33972);ArGME2(lcl|BJWL01000003.1_prot_GFY85020.1_4829) |
| 阔叶猕猴桃(Actinidia latifolia) | AlfGME1(Alf24g10200KY);AlfGME2(Alf03g02310KY);AlfGME3(Alf01g09810KY) |
| 苹果(Malus domestica) | MdGME1(mRNA:MD04G1224200);MdGME2(mRNA:MD12G1240900);MdGME3(mRNA:MD04G1224100) |
| 梨(Pyrus pyrifolia) | PbGME1(Pspp.Chr04.01901.1);PbGME2(Pspp.Chr12.01931.1) |
| 桃(Prunus persica) | PpGME1(P124PAN22681);PpGME2(P124PAN14140) |
| 刺梨'贵农5号' (Rosa roxburghii Tratt 'Guinong5') |
RrGME1(Rrox7g_035880.1);RrGME2(Rrox6g_002750.1) |
| 枣(Ziziphus jujuba) | ZjGME1(rna-XM_016019918.4);ZjGME2(rna-XM_016020989.4) |
| 甜橙(Citrus sinensis) | CitGME1(Cit_ont_3g019420.4);CitGME2(Cit_ont_9g006640.1) |
| 晚白柚(Citrus maxima) | CitGME1(Cg3g010360.1);CitGME2(Cg9g006520.1) |
| 椪柑(Citrus reticulata) | CitGME1(Ponkan3g0018570.1);CitGME2(Ponkan9g0008180.1) |
| 枳壳(Poncirus trifoliata) | CitGME1(Pt5g016700.1);CitGME2(Pt9g006200.1) |
| 枸橼(Citrus medica L) | CitGME1(Cit127250.1);CitGME2(Cit303610.1);CitGME3(Cit286230.1);CitGME4(Cit067090.1);CitGME5(Cit311200.1) |