磷酸甘露糖变位酶 (PMM)
磷酸甘露糖变位酶(phosphomannomutase, PMM)催化6-磷酸-甘露糖和1-磷酸-甘露糖之间的转化, 1-磷酸-甘露糖进一步形成GDP-甘露糖，参与蛋白翻译后修饰(提供糖基化蛋白寡糖核心)和植物中抗坏血酸(AsA)的合成
phosphomannomutase(PMI)
Phosphomannose isomerase (PMI) plays a crucial role in the biosynthesis of ascorbic acid (AsA), also known as vitamin C, by catalyzing the conversion of mannose-6-phosphate (Man-6-P) to fructose-6-phosphate (Fru-6-P) or, alternatively, enabling the interconversion between these two sugars in a reversible manner. While the primary pathway for AsA biosynthesis in plants involves the L-galactose pathway, PMI contributes indirectly by regulating the availability of GDP-mannose, a key precursor in the pathway.
| 拟南芥(Arabidopsis thaliana) | AtPMM | Protein |
|---|---|---|
| 番茄(Solanum Lycopersicum) | SLPMM1(Solyc08g008670.3.1) | MAARKAGLIALFDVDGTLTAPRKESTPQMLKFMQELRKVVTVGVVGGSDLVKISEQLGNTVTNDYDYVFSENGLVAHKDGKLIGKQSLKSHLGDEKLKEFINFTLHYIADLDIPIKRGTFIEFRSGMLNVSPIGRNCSQEERDEFEKYDKAQKIRETMVSVLREKFAHFNLTFSIGGQISFDVFPQGWDKTYCLRYLEEFNEIHFFGDKTYKGGNDHEIYESERTVGHTVTSPEETLKQCSVLFLGKDNGSS |
| SLPMM2(Solyc05g046340.2.1) | MRARKAGLIALFDVDGTLTAPRKECTPEMLKFMRELRKVVTIGVVGGSDLVKISEQLGSSVMNDYDYVFSENGLVAHKDGKLIGKQSMKSFLGDEKLKEFINFTLCYIADLDIPIKRGTFIEFRSGMLNVSPIGGNCSQEEREEFVKYDKVQKIRETMISVLRGKFAHLNLTFSIGGQISFDVFPQGWDKTYCLRYLEEFNEIHFFGDKTYKGGNDHEIYESKRTVGHTITSPEDTMKQCFVLFFDKDNGTL | |
| SLPMM3(Solyc05g048760.3.1) | MAARKAGLIALFDVDGTLTAPRKESTPQMLKFMQELRKVVTVGVVGGSDLVKISEQLGNTVTKDYDYVFSENGLVAHKDGKLIGKQSLKSYLGDEKLKEFINFTLHYIADLDIPIKRGTFIEFRSGMLNVSPIGRNCSQEERDEFEKYDKVQKIRETMVSVLREKFAHFNLTFSIGGQISFDVFPQGWDKTYCLRYLEEFNEIHFFGDKTYKGGNDHEIYESERTVGHTVTSPEETLKQCSVLFLGKDNGSS | |
| SLPMM4(Solyc08g076550.3.1) | MCRLLGGTVARDEFEKYDKVQKMRETLVSVLREKFAHFNLTFSIGGQISFDVLPQGWDKTYCLRYLEEFNEIHFFGDKTYKAPIGVCHQSPFPGLRNLVRDAAVFGDTNLELPSFLSNRSLVEVHLEVGTNLTSQQKDELEIHMELPLHARYQPLGHGFSRVEFASPDLFLRCNLERKEYDTGCLFLLDKQNAESIDTHPVWEVPCGNREHTEVVSAFTFISALVSALLIIVASIKCI | |
| SLPMM5(Solyc08g076560.1.1) | MRAVTNDYDYVFSENGLVAHKDGKLIRKQSLLSYLGDEKLKVSQYVFLI | |
| 葡萄(Vitis vinifera) | VvPMM(XP_034710027.1) | MAARKAGLIALFDVDGTLTAPRKVATPQMLEFMRKLRKVITVGVVGGSDLVKISEQLGSSVIDDYDYVFSENGLVAHKDGKLIGTQSLKTFLGEEKLKEIINFTLHYIADLDIPIKRGTFIEFRSGMLNVSPIGRNCSQEERDEFEKYDKIHNIRPKMVSVLREKFAHLNLTFSIGGQISFDVFPQGWDKTYCLRYLDDFPEIHFFGDKTYKGGNDHEIYESERTVGHTVTSPDDTVEQCAALFLAKSS |
| 中华猕猴桃'红阳' (Actinidia chinensis cv 'Hongyang') |
AcPMM(Actinidia09997.t1) | MLLGHSSSISDLLQPLDSHYIPRSPPFRHQISLRNFCILKMEARKPGVIALFDVDGTLTAPRKAATPDMLNFMRELQKVVTIGVVGGSDLVKISEQLGKSVINDYDYAFSENGLVAYKDGKLIGTQSLKSHLGEEKLKELINFTLHYIADLDIPIKRGTFIEFRSGMLNASPIGRNCSQEERDEFERYDKVHNIRPKMVSVLREKFSHLNLTFSIGGQISFDVFPQGWDKTYCLRYLDDFHEIHFFGDKTYKGGNDFEIYESERTMGHTVTSPEDTVQQCTDLFLSKQV |
| 中华猕猴桃'Red5' (Actinidia chinensis cv 'Red5') |
AcPMM(Acc09107.1) | MLLGHSSSISDLLQPLDSHYIPRSPPFRHQISLRNFCILKMEARKPGVIALFDVDGTLTAPRKAATPGMLNFMRELRKVVTIGVVGGSDLVKISEQLGKSVINDYDYAFSENGLVAYKDGKLIGTQSLKSHLGEEKLKELINFTLHYIADLDIPIKRGTFIEFRSGMLNVSPIGRNCSQEERDEFERYDKVHNIRPKMVSVLREKFSHLNLTFSIGGQISFDVFPQGWDKTYCLRYLDDFHEIHFFGDKTYKGGNDFEIYESERTMGHTVTSPEDTVQQCTDLFLSKQV |
| 中华猕猴桃'东红' (Actinidia chinensis cv 'Donghong') |
AcPMM(Ach08g08540DH) | MLLGHSSSISDLLQPLDSHYIPRSPPFRHQISLRNFCILKMEARKPGVIALFDVDGTLTAPRKAATPGMLNFMRELRKVVTIGVVGGSDLVKISEQLGKSVINDYDYAFSENGLVAYKDGKLIGTQSLKSHLGEEKLKELINFTLHYIADLDIPIKRGTFIEFRSGMLNVSPIGRNCSQEERDEFERYDKVHNIRPKMVSVLREKFSHLNLTFSIGGQISFDVFPQGWDKTYCLRYLDDFHEIHFFGDKTYKLPARKTQYSSVPISSYPSKSDLPESTAVKDTPRQYPMAEVEVADQNPRFFVAVHVGAGFHAPSNEKALRSTMKRACVAAAAVLRKGPGGCIDAVSAALQVLEDDPSTNAGRGSNLTEDGHVECDASVMDGDSGAFGAVGAVPGVWNGIQLAALLAKEQMLGTSLLGRIPPIFLVGEGARVWAKSKGISLPSSIEESDKWLITERAKRQWEKYKAMLDEAKAMTACSHIELSSGPQENAVVSGIEAQPCDHLDANGNHDLPSTLNAPEDDCIMDTVGVICVDSEGHIASGASSGGIALKVSGRVGLAAMYGSGCWASSKGPFGAPFIVGCCVSGAGEYLMKGFAARECCVSSS |
| 毛花猕猴桃'华特' (Actinidia eriantha cv 'White') |
AePMM(DTZ79_08g09630) | MEARKPGVIALFDVDGTLTAPRKVATPDMLNFMGELRKVVTIGVVGGSDLVKISEQLGKSVINDYDYAFSENGLVAYKDGKLIGTQSLKSHLGEEKLKELINFTLHYIADLDIPIKRGTFIEFRSGMLNVSPIGRNCSQEERDEFERYDKVHNIRPKMVSVLREKFSHLNLTFSIGGQISFDVFPQGWDKTYCLRYLDDFHEIHFFGDKTYKLPARKTQYSSVLISSYPSKSDLPEVISTLLPSK |
| 野生毛花猕猴桃 (Actinidia eriantha WT) |
AePMM1(evm.model.scaf_35.17) | MDSWCLVLNFGTIVTEMALGGAAPQRGSAAAAAANLRRRRTTSGGGAAGGASGTMLQFYTDDAPGLKISPNVVLVMSIGFIAFVAILHVMGKLYFVRREA |
| AePMM2(evm.model.scaf_34.93) | MEARKPGVIALFDVDGTLTAPRKVATPDMLNFMGELRKVVTIGVVGGSDLVKISEQLGKSVINDYDYAFSENGLVAYKDGKLIGTQSLKSHLGEEKLKELINFTLHYIADLDIPIKRGTFIEFRSGMLNVSPIGRNCSQEERDEFERYDKVHNIRPKMVSVLREKFSHLNLTFSIGGQISFDVFPQGWDKTYCLRYLDDFHEIHFFGDKTYKGGNDFEIYESERTKGHTVTSPEDTVQQCTDLFLSKQV | |
| 毛花猕猴桃'赣绿1号' (Actinidia eriantha cv 'Ganlv1') |
AePMM(Chr_02G823.1) | MEARKPGVIALFDVDGTLTAPRKVATPDMLNFMGELRKVVTIGVVGGSDLVKISEQLGKSVINDYDYAFSENGLVAYKDGKLIGTQSLKSHLGEEKLKELINFTLHYIADLDIPIKRGTFIEFRSGMLNVSPIGRNCSQEERDEFERYDKVHNIRPKMVSVLREKFSHLNLTFSIGGQISFDVFPQGWDKTYCLRYLDDFHEIHFFGDKTYKGGNDFEIYESERTKGHTVTSPEDTVQQCTDLFLSKQV |
| 山梨猕猴桃(Actinidia rufa) | ArPMM(lcl|BJWL01000008.1_prot_GFY92588.1_12397) | MRYQWQVATPDMLNFMRELRKVVTIGVVGGSDLVKISEQLGKSVINDYDYAFSENGLVAYKDGKLIGTQSLKSHLGEEKLKELINFTLHYIADLDIPIKRGTFIEFRSGMLNVSPIGRNCSQEERVEFERYDKVHNIRPKMVSVLREKFSHLNLTFSIGGQISFDVFPQGWDKTYCLRYLDDFHEIHFFGDKTYKLPARKTQYCSVPISSYPSKSDLPEVISTLLPSN |
| 阔叶猕猴桃(Actinidia latifolia) | AlfPMM(Alf08g08390KY) | MAESIASTATKRYAVVTGANKGIGFEICRQLASNGVMVVLTARDEKRGCDALEKFKGFGLSELVVFHQLDVADPSSIASLADFVKTLFGRLDILVNNAGISGAMIDWDAFESQAGGAGSGGQVNWNELMNQSYELTKACLETNYYGAKRMIEAFHPLLQLSDSPRIVNVSSAMSKLKNIPSEWAKGVLSDANSLTEERVDEVLNKFLKDFQENSIETGGWPSFLSAYTVSKAAMNAYTRIAAKKYPNFLINCVCPGFVKTDINNNSGSLSVEEGALCPVRLALLPDDGPSGLFFIRNENIPGEWVRGVVRDAESLTEERVDEENSAARDVSTYTWTTFFTPIACHAVATPDMLNFMRELRKVVTIGVVGGSDLVKISEQLGKSVINDYDYAFSENGLVAYKDGKLIGTQSLKSHLGEEKLKELINFTLHYIADLDIPIKRGTFIEFRSGMLNVSPIGRNCSQEEREEFERYDKVHNIRPKMVSVLCEKFSHLNLTFSIGGQISFDVFPQGWDKTYCLRYLDDFHEIHFFGDKTYKFLTLWELKDGSGCCLSREEMTSRYMNQSKQWVIQLPARKTQYSSVPISSYPSKSDLPEAIGIFMFPLFIRRFNLSFLRALEEPYVGMFGFSRCYLEYSLQPLKDTPQQYPMAEVEVSDQNPRFFVTVHVGAGFHAPSNEKALRSAMKRACLAAAAVLRKGPGGCIDAVSAALQVLEDDPSTNAGRGSNLTEDGHVECDASVMDGDSGAFGAVGAVPGVWNGIQLAALLAKEQMLGTSLLGRIPPIFLVGEGARVWAKSKGIPLPSSIEEADKWLVTERAKRQWEKYKAMLDEAKAMTACSHIELSSGPQENAAISGIEAQPCDHLDANGNHDLPSTLNAPEDDCIMDTVGVICVDSEGHIASGASSGGIALKVSGRVGLAAMYGSGCWASSKGPFGAPFIVGCCVSGAGEYLMKGFAARECCVSSSLSQAGPVSGCTKVLRSVIQGSGQHGTDKSAGILIVQADAPITLPGNSPKLKAIEIAAAYTSLSFGIGYFGSSMERPKVSILRSAKQQNRAGIDQFAARIDLSAK |
| 苹果(Malus domestica) | MdPMM1(mRNA:MD01G1053400) | MAVRRPGVLALFDVDGTLTAPRKVVTPEMLEFMRELRKIVTVGIVGGSDLSKITEQLGKTVIDDHDYVFSENGLVAHKDRTLIGTQSLKTYLGEDKLKEFINFTLHYIADLDIPIKRGTFIEFRSGMLNVSPIGRNCSQEERDEFERYDKVQNIRPKMVSVLREKFGHLNLTFSIGGQISFDVFPHGWDKTYCLRYLDDFQEIHFFGDKTYKGGNDHEIYESERTVGHTVTSPEDTIKQCTALFLSP |
| MdPMM2(mRNA:MD07G1141700) | MAVRRPGVIALFDVDDTLTAPRKFVTPEMLECMRELRKVVTVGIVGGSDLTKITEQLGKTVIDDYDYVFTENGLVAHKDRTLIGTQSLKTYLGEDKLKEFINFTLHYIADLDIPIKRGTFIEFRSGMLNVSPIGRNCSQEERDEFERYDKVQNIRPKMVSVLREKFGHLNLMFSIGGQISFDVFPQGWDKTYCLRYLDDFQEIHFFGDKTYKGGNDHEIYESERTVGHTVTNPEDTIKQCTALFLNP | |
| 梨(Pyrus pyrifolia) | PbPMM1(Pspp.Chr07.01151.1) | MDVRRPGVIALFDVDDTLTAPRKDVTPEMLELMRELRKVVTVGIVGGSDLSKITEQLGKTVMDDYDYVFSENGLVAHKDRTLIGTQSLKTYLGEDKLKEFINFTLHYIADLDIPIKRGTFIEFRNGMLNVSPIGRNCSQEERDEFERYDKVQNIRPKMVSMLREKFGHLNLTFSIGGQISFDVFPQGWDKTYCLRYLDDFQEIHFFGDKTYKGGNDHEIYESERTVGHTVTSPEDTIKQCTALFLNP |
| PbPMM2(Pspp.Chr01.00583.1) | MAVRRPGVLALFDVDGTLTAPRKVVTPEMLGFMRELRKVVTVGIVGGSDLSKITEQLGKTVIDDHDYVFSENGLVAHKDRTLIGTQSLKTYLGEDKLKEFINFTLHYIADLDIPIKRGTFIEFRSGMLNVSPIGRNCSQEERDEFEKYDKVQNIRPKMVSVLREKFGHLNLTFSIGGQISFDVFPQGWDKTYCLRYLDDFQEIHFFGDKTYKGGNDHEIYESERTVGHTVSSPEDTIKQCTALFLSP | |
| 桃(Prunus persica) | PpPMM1(P124PAN01460) | MAVRKPGVIALFDVDGTLTAPRKAVTPEMLGFIRELRKAVTVGIVGGSDLSKITEQLGRTVIDDYDYVFSENGLVAHKDRTLIGTQSLKTFLGEEKLKEFINFTLHYIADLDIPIKRGTFIEFRSGMLNVSPIGRNCSQEERDEFERFDKVQNIRPKMVSILREKFAHLNLTFSIGGQISFDVFPQGWDKTYCLRYLEKFQEIHFFGDKTYKGGNDHEIYESERTVGHTVTSPEDTIKQCKALFLSP |
| PpPMM2(P124PAN03175) | MLDFMRELRKVVTVGIVEGSDLSKITEQLGKTGSLKTFLGEEKLKIKPCSVVCYDSQVQNTRPKMVSVLREKFAHLNLTFSIGGQISFDVFPPGWDKTYCLRYLEDFQEIHFFGDKTYKGGNDHEIYESERTVAHTVISPEDTAKQCKAVFLSPRYRSNFSVLCYTPFSNKNKLYAICNSVFENKC | |
| 刺梨'贵农5号' (Rosa roxburghii Tratt cv 'Guinong5') |
RrPMM1(Rrox5g_021930.1) | MDVMKPGVIALFDVDGTLTAPRKDVTPQMLGFMRELRKVVTVGIVGGSNLSKITEQLGKTVMGDYDYVFSENGLVAHKDGKLIGTQSLKSHLGDDKLKEFINFTLHYIADLDIPIKRGTFIEFRSGMINVSPIGRNCSQEERDEFERYDKVHNVRPKMISILREKFAHFNLTFSIGGQISFDVFPQGWDKTYCLRYLEEFQEIHFFGDKTYKGGNDHEIYESERTVGHTVTSPEDTVEQCKALFFSR |
| RrPMM2(Rrox3g_022440.1) | MVVTKPGVIALFDVDGTLTAPRKDVTPQMLGFMRELKKVVTVGIVGGSNLSKITKQLGNTELQRTNLELDSYKEKIKENQEKINLNKQLPYLVGNIVEILEMNPEDEAEENGANIDIGGLWRLMRNQLKITMILEG | |
| RrPMM3(Rrox2g_062310.1) | MAVTKPGVIALFDVDGTLTAPRKDVTPQMLGFMRELKKVVTVGIVGGSNLSKITKQLGNTELQRTNLELDSYKEKIKENQEKINLNKQLPYLVGNIVEILEMNPEDEAEENGANIDIGGLWMSGDREVQRTMLELLNQLDGFSSDDRIKVIATTNHADILDPALMRSGRLDRKIEFPHPTEEARARIMQIHSRKMNVHPDVNFEELARSTIDSMVHN | |
| RrPMM4(Rrox6g_003880.1) | MRELKKVVTVGIVGGSNLSKITKQLGNTELQRTNLELDSYKEKIKENQEKINLNKQLPYLVGNIVEILEMNPEDEAEENGANIDIGGLWMSGDREVQRTMLELLNQLDGFSSDDWIKVIAATNHADILDPALMRSGRLDRKIEFPHPTEEARALIMQIHSRKMNVHPDVNFEELARSTVDSMVHN | |
| 枣(Ziziphus jujuba) | ZjPMM(rna-XM_016033131.4) | MALPKQGVIALFDVDGTLTAPRKDSTPQMLEFMRELRKVVTVGVVGGSDFSKVNEQLGKTVLDDYDYVFTENGLVAHKGGKLIGTQNLKSFLGEEQLKEFINFTLHYIADLDIPIKRGTFIEFRNGMLNVSPIGRNCSQEERDEFEKYDKIHNIRPKMISVLQEKFAHLNLTFSIGGQISFDVFPHGWDKTYCLRYLDDFPEIHFFGDKTYKGGNDHEIYESERTIGHTVTSPEDTVEQCKALFLVKS |
| 甜橙(Citrus sinensis) | CitPMM(Cs_ont_5g002800.1) | MAARKQGLLALFDVDGTLTAPRKAATPQMLEFMRELRKVVTVGVVGGSDLSKISEQLGKTVIDEYDYVFSENGLVAHKDGKLIGTQSLKSFLGGEKLKEFINFTLHYIADLDIPIKRGTFIEFRSGMLNISPIGRNCSQEERDEFERYDKIHNIRPKMVSVLREKFAHLNLTFSIGGQISFDVFPQGWDKTYCLRYLDDFNEIHFFGDKTYKGGNDHEIFESERTVGHTVTSPEDTMEKCKALFLAKP |
| 晚白柚(Citrus maxima) | CitPMM(Cg5g042400.1) | MAARKQGLLALFDVDGTLTAPRKAATPQMLEFMRELRKVVAVGVVGGSDLSKISEQLGKTVIDEYDYVFSENGLVAHKDGKLIGTQSLKSFLGDEKLKEFINFTLHYIADLDIPIKRGTFIEFRSGMLNISPIGRNCSQEERDEFERYDKIHNIRPKMVSVLREKFAHLNLTFSIGGQISFDVFPQGWDKTYCLRYLDDFNEIHFFGDKTYKGGNDHEIFESERTVGHTVTSPEDTMEKCKALLLAKP |
| 椪柑(Citrus reticulata) | CitPMM(Ponkan5g0017950.1) | MAARKQGLLALFDVDGTLTAPRKAATPQMLEFMRELRKVVTVGVVGGSDLSKISEQLGKTVIDEYDYVFSENGLVAHKDGKLIGTQSLKSFLGGEKLKEFINFTLHYIADLDIPIKRGTFIEFRSGMLNISPIGRNCSQEERDEFERYDKIHNIRPKMVSVLREKFAHLNLTFSIGGQISFDVFPQGWDKTYCLRYLDDFNEIHFFGDKTYKGGNDHEIFESERTVGHTVTSPEDTMEKCKALFLAKP |
| 枳壳(Poncirus trifoliata) | CitPMM(Pt3g038840.1) | MAARKQGLLALFDVDGTLTAPRKAATPQMLEFMRELRKVVTVGVVGGSDLSKISEQLGKTVIDEYDYVFSENGLVAHKDGKLIGTQSLKSFLGDEKLKEFINFTLHYIADLDIPIKRGTFIEFRSGMLNISPIGRNCSQEERDEFERYDKIHNIRPKMVSVLREKFAHLNLTFSIGGQISFDVFPQGWDKTYCLRYLDDLNEIHFFGDKTYKGGNDHEIFESERTVGHTVTSPEDTMEKCKALFLAKP |
| 枸橼(Citrus medica L) | CitPMM(Cm226580.1) | MAARKQGLLALFDVDGTLTAPRKAATPQMLEFMRELRKVVTVGVVGGSDLSKISEQLGKTVIDEYDYVFSENGLVAHKDGKLIGTQSLKSFLGDEKLKEFINFTLHYIADLDIPIKRGTFIEFRSGMLNISPIGRNCSQEERDEFERYDKIHNIRPKMVSVLREKFAHLNLTFSIGGQISFDVFPQGWDKTYCLTYLDDFNEIHFFGDKTYKGGNDHEIFESERTVGHTVTSPEDTMEKCKALFLAKP |